You only have to step on the center tile to get it to roll (in my experience), so you can run around the edges and open the two or four chests, then reroll it all and potentially get good stuff like more chests or black hearts or something.
Isaac Dice Room: 5 Tips To Unlock Your Full Potential!
You only have to step on the center tile to get it to roll (in my experience), so you can run around the edges and...